IL-1 beta anticorps
Aperçu rapide pour IL-1 beta anticorps (ABIN299326)
Antigène
Voir toutes IL-1 beta (IL1B) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Recognizes human IL-1 beta. Neutralizes the biological activity of recombinant humanIL-1b and natural human IL-1b. Will not neutralize the biological activity of recombinant mouse IL-1b, recombinant human IL-1a, or recombinant mouse IL-1a. Based on direct ELISA results, this antibody shows less than 10 % cross-reactivity with recombinant mouse IL-1b, recombinant porcine IL-1b, recombinant rat IL-1b and recombinant crIL-1b.
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Purification
- Immunoaffinity purified
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Immunogène
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Recombinant human IL-1 beta.
Type of Immunogen: Recombinant protein -
Isotype
- IgG
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Indications d'application
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Approved: ELISA (0.5 - 1 μg/mL), Neut, WB (0.1 - 0.2 μg/mL)
Usage: Suitable for use in ELISA, Western Blot, and Neutralization of bioactivity. Direct ELISA: 0.5-1 μg/mL. Detection limit for rhIL-1bis ~1.5 ng/well. Western Blot: 0.1-0.2 μg/mL. Detection limit for rhIL-1b is ~0.5 ng/lane under both non-reducing and reducing conditions. -
Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Sterile PBS
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Concentration
- Lot specific
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Buffer
- Lyophilized from PBS, 5 % trehalose
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Conseil sur la manipulation
- Avoid freeze-thaw cycles.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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Autre désignation
- IL1B
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Sujet
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Name/Gene ID: IL1B
Family: IL-1
Synonyms: IL1B, IL-1B, IL-1 beta, IL1-BETA, Preinterleukin 1 beta, Pro-interleukin-1-beta, Catabolin, IL-1, IL1F2, Interleukin 1, beta, Interleukin-1 beta -
ID gène
- 3553
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UniProt
- P01584
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Pathways
- Signalisation NF-kappaB, Interferon-gamma Pathway, Signalisation TLR, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
Antigène
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